Improved feeding in tilapia and seabream using genome editing
Research project 12
Project researchers: Dr. Jakob Biran and Dr. Amir Bitan

The increased demand for fish, alongside the reduction in fish abundance in the seas and lakes, drives the expansion of fish farming. There is a need to rely more on sustainable feed resources to support the rapid growth of aquaculture and reduce the use of fishmeal as a primary ingredient in fish feed. However, alternative and more sustainable feed ingredients may reduce feeding and growth. Several works have demonstrated that blockage of anorexigenic factors in fish can result in increased feeding behavior. This study strives to perform genome editing to improve feeding behavior in two major aquaculture species – Nile tilapia and Gilthead seabream.

מחקר מס' 12 – יעקב בירן ועמיר ביתן
Nile tilapia in the fishery of Volcani
Research project 12 - Dr. Jakob Biran and Dr. Amir-Bitan
Fish feed ingredients

A successful outcome of this research may allow the increased use of sustainable feed components for fish aquaculture and reduce the costs and growth times of farmed fish.

Dr. Jakob (Kobi) Biran 
Project researcher

Animal Science, Agricultural Research Organization, Volcani Institute.


Phone: +972-54-2260501

Website: Dr. Jakob (Kobi) Biran

Research areas:

  • Genome editing in fish.
  • Neuroendocrine regulation of fish metabolism.
  • Neuroendocrine regulation of stress in fish.
Dr. Amir-Bitan

Dr. Amir Bitan 
Project researcher

Israel Oceanographic & Limnological Research.


Phone: +972-52-6054990

Website: Dr. Amir-Bitan

Research areas:

  • Fish nutrition.
  • Digestion and nutrient absorption in farmed fish.
  • Optimization of fish feed formulations.
  • Development of screening platforms for novel feed ingredients and functional feeds for aquaculture.

Research partners:

Adi Segev-Hadar

Adi Segev-Hadar
Research Associate

Agricultural Research Organization, Volcani Institute.

ניקו אלווין קבילון

Nikko Alvin Cabillon
Ph.D. student

Agricultural Research Organization, Volcani Institute and The Hebrew University.

ליאת קוך

Dr. Liat Koch
Postdoctoral researcher

Israel Oceanographic & Limnological Research.

נועם מזרחי

Noam Mizrachi
MSc student

Israel Oceanographic & Limnological Research and Ben-Gurion University of the Negev.